| Title | [Mastocytosis : A challenge in anaesthesiology.] | | Author(s) | Konrad FM, Unertl KE, Schroeder TH | | Institution | Klinik für Anaesthesiologie und Intensivmedizin, Universitätsklinikum Tübingen, Tübingen, Deutschland. | | Source | Anaesthesist 2009 Oct 2. | | Abstract | Mastocytosis is a general term for a heterogeneous group of rare disorders. Many agents used in anaesthesia can trigger mast cell degranulation with release of histamine, prostaglandin, tryptase and heparin. Therefore, patients with mastocytosis are high-risk patients when undergoing anaesthesia. The management of these patients in anaesthesia will be discussed on the basis of the literature and illustrated with the discussion of three case reports. A premedication with antihistamines and a glucocorticoid is recommended. For induction of general anaesthesia propofol, etomidate, ketamine, a fentanyl-type opioid, cis-atracurium or pancuronium are recommended. Anaesthesia can be maintained either by a total intravenous technique or with a volatile anaesthetic such as sevoflurane. | | Language | GER | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19795098 |
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